Top Choice Hotels in Florence, SC

We checked thousands of reviews on and to find the best hotels for your stay
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Alardo Riojas

Updated: 20 February 2024 · 5 min

Nestled in the lively heart of South Carolina, Florence emerges as a vibrant hub that captivates visitors with its blend of culture, history, and Southern charm. For travelers looking to immerse themselves in this enchanting locale, staying at one of the many Choice Hotels in Florence offers an unparalleled comfort and convenience. These accommodations provide not only a gateway to exploring the city’s treasures but also a promise of quality, reliability, and excellent service to enhance your travel experience.

As you plan your visit, considering a Choice Hotel as your home away from home allows you to focus on crafting the perfect itinerary. Whether you're in town for business or leisure, these hotels are strategically located near Florence's key attractions, dining, and shopping areas. Their wide range of options, from budget-friendly to upscale, ensures that every traveler finds a tailored fit that meets their needs, making your stay in Florence both enjoyable and memorable.

Moreover, Choice Hotels in Florence are renowned for their hospitality and attention to detail, ensuring your time in the city is as stress-free as possible. With amenities designed to make your stay comfortable, like complimentary breakfasts, free WiFi, and swimming pools, guests can truly relax after a day of exploration. This focus on providing a stellar guest experience makes Choice Hotels the go-to option for many who visit Florence, promising an unforgettable journey into the heart of South Carolina.
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Our Top 9

(Sorted by rating & number of reviews)

1. Quality Inn Florence Muscle Shoals
2. Marriott Shoals Hotel & Spa
3. Days Inn By Wyndham Florence Downtown
4. Hampton Inn & Suites-Florence Downtown
5. Gunrunner Boutique Hotel
6. Residence Inn By Marriott Florence
7. Baymont By Wyndham Florence/Muscle Shoals
8. Comfort Suites Florence Shoals Area
9. The Stricklin Hotel- Florence

Choice Hotels Florence SC: Family-Friendly Stays

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Florence
Jan 28, 2026 - Jan 29, 2026

Quality Inn Florence Muscle Shoals

6.3

Good

(179 Reviews)

+ 67 photos
Quality Inn Florence Muscle Shoals provides an excellent value proposition, combining affordable rates with essential amenities that every traveler appreciates. With a complimentary breakfast to start the day, free Wi-Fi for staying connected, and an outdoor pool for relaxation, guests are ensured a comfortable stay. Its proximity to local attractions also makes it a convenient option for those looking to explore Florence without breaking the bank.
Address: 150 Etta Gray Drive
Rating: Good 6.3 (179 Reviews)
Rooms: 47
Price: From 75$

Marriott Shoals Hotel & Spa

8.7

Good

(242 Reviews)

+ 147 photos
The Marriott Shoals Hotel & Spa combines luxury with practicality, making it a top pick for business travelers. With its well-equipped business center, versatile meeting spaces, and high-speed internet, professionals can easily manage work commitments. The hotel also features a spa, outdoor and indoor pools, and several dining options, providing ample opportunities to relax and recharge. Its location offers beautiful views of the Tennessee River, adding a touch of serenity to your business trip.
Address: 10 Hightower Place
Rating: Good 8.7 (242 Reviews)
Rooms: 199
Price: From 143$

Choice Hotels Florence SC: Business and Conference-Friendly

Business travelers and conference attendees often seek convenience, comfort, and efficient services during their stays. Florence hosts a selection of Choice Hotels that cater specifically to the needs of the business community. These hotels offer amenities such as business centers, meeting rooms, and high-speed internet access, ensuring that work can continue seamlessly outside of the office. For professionals looking for accommodation that balances work requirements with relaxation, the following hotels stand out.

Days Inn By Wyndham Florence Downtown

7.1

Good

(54 Reviews)

+ 36 photos
Situated closer to the heart of Florence by Wyndham Florence Downtown offers an economical stay with direct access to the city’s vibrant center. The hotel doesn’t skimp on essentials, providing free Wi-Fi, comfortable rooms, and attentive service. Its location is ideal for travelers wanting to soak in the city’s atmosphere and attractions without overspending on accommodation.
Address: 400 S Court St
Rating: Good 7.1 (54 Reviews)
Rooms: 86
Price: From 68$

Hampton Inn & Suites-Florence Downtown

8.6

Good

(189 Reviews)

+ 132 photos
Nestled in the heart of Florence, the Hampton Inn & Suites-Florence Downtown is another excellent choice for families. Its downtown location places guests close to museums, parks, and dining options suited for every palate. The hotel features comfortable rooms with modern amenities, a complimentary breakfast buffet that kids will love, and a pool for refreshing swims. Their exceptional service and attention to detail make staying here a pleasure, providing a cozy retreat after a day of exploring Florence's charm.
Address: 505 South Court Street
Rating: Good 8.6 (189 Reviews)
Rooms: 88
Price: From 116$

Choice Hotels Florence SC: Budget-Friendly Options

Affordability without compromising on comfort and quality is key for many travelers. Florence provides various Choice Hotels that cater to budget-conscious visitors, offering them a cost-effective way to enjoy their stay. These accommodations boast amenities such as complimentary breakfast, free Wi-Fi, and prime location—all wrapped in an economical package. For travelers looking to stretch their dollars further while exploring what Florence has to offer, these hotels present an attractive proposition.

Gunrunner Boutique Hotel

9.3

Good

(29 Reviews)

+ 65 photos
Gunrunner Boutique Hotel offers a unique experience with its individually themed rooms, each telling a different story. This hotel is perfect for couples looking for an intimate and distinctive stay. The attention to detail, luxurious amenities, and bespoke service ensure a memorable romantic getaway. Its convenient location allows easy exploration of Florence’s romantic spots, making it a preferred choice for lovebirds.
Address: 310 E Tennessee St
Rating: Good 9.3 (29 Reviews)
Rooms: 34
Price: From 277$

Residence Inn By Marriott Florence

8.4

Good

(62 Reviews)

+ 27 photos
For families wishing for home-like comfort, the Residence Inn by Marriott Florence offers well-appointed suites with fully equipped kitchens. This hotel knows the importance of space and convenience for families, featuring separate living, sleeping, and cooking areas. Guests can take advantage of the outdoor pool, enjoy the daily complimentary hot breakfast, and attend the evening socials on select nights. Located close to educational and recreational spots, it provides an ideal home base for family adventures in Florence.
Address: 1000 Sweetwater Avenue
Rating: Good 8.4 (62 Reviews)
Rooms: 110
Price: From 113$

Choice Hotels Florence SC: Romantic Getaways

For couples seeking a romantic escape, Florence harbors several Choice Hotels that specialize in creating an intimate ambiance. These accommodations offer special amenities like luxurious suites, picturesque views, and proximity to romantic dining spots and activities. Whether celebrating an anniversary, a honeymoon, or simply a much-needed getaway, couples can find the perfect backdrop for their romantic retreat within these selected hotels.

Baymont By Wyndham Florence/Muscle Shoals

7.2

Good

(499 Reviews)

+ 62 photos
Offering competitive pricing without sacrificing cleanliness and comfort, Baymont by Wyndham Florence/Muscle Shoals is a testament to budget-friendly lodging. Guests can enjoy basics like free Wi-Fi and breakfast, as well as the convenience of being located near major attractions and dining options in Florence. The hotel’s friendly staff and comfortable rooms make it a solid choice for travelers watching their wallet.
Address: 115 Ana Dr
Rating: Good 7.2 (499 Reviews)
Rooms: 64
Price: From 76$

Comfort Suites Florence Shoals Area

8.4

Good

(370 Reviews)

+ 98 photos
A prime example of family-friendly accommodation is the Comfort Suites Florence Shoals Area. This hotel goes above and beyond to make families feel at home, offering spacious suites that provide enough room for everyone. Guests can enjoy a daily complimentary breakfast, an indoor pool perfect for any season, and a fitness center. The hotel's proximity to family attractions like the Florence Sports Complex makes it an ideal base for exploring the area. The attentive staff and kid-friendly amenities ensure that your family's stay in Florence will be comfortable and enjoyable.
Address: 140 Matthew Paul Court
Rating: Good 8.4 (370 Reviews)
Rooms: 68
Price: From 121$

The Stricklin Hotel- Florence

8.2

Good

(247 Reviews)

+ 17 photos
The Stricklin Hotel, nestled in the charming downtown Florence, sets the stage for a romantic getaway with its carefully curated experience. The hotel combines the allure of historic architecture with modern luxury, offering stylish rooms that serve as a cozy haven for couples. With gourmet dining options on-site and a bustling nightlife just steps away, The Stricklin Hotel makes for an idyllic romantic escape.
Address: 317 North Court Street
Rating: Good 8.2 (247 Reviews)
Rooms: 24
Price: From 149$